Analytical Chemistry

This team provides support to discovery and process chemistry group as integrated services or as stand-alone entity to customer demands.

The various services offered in this are:

Purification

  • Isolation, purification and characterization of compounds from mg to gram level.
  • Chiral purification.
  • High throughput purification services
  • Natural product and dendrimers type purification

Structure Elucidation of Small Molecules

  • Structure elucidation of new chemical entities (NCEs) by mass spectrometry, NMR (1H, 13C, 19F, 11B, 15N), IR and UV-Visible spectrophotometry.
  • Higher NMR experiments like NOESY, HMBC, HMQC etc.
  • MS, MS-MS, LCMS, HRMS.

Physicochemical Study

  • Melting point
  • Solubility
  • pKa
  • Log P determination
  • Optical rotation
  • Elemental analysis
  • Stability studies by HPLC
  • Polymorphism
  • DSC and TGA

Regular analysis to support all chemistry services

  • Routine NMR/LCMS/MS/HPLC is produced and delivered and stored through proprietary e-analytic software/database.

Impurity Profiling

  • Isolation of impurity
  • Structure elucidation
  • Data support with minute quantity

Prelinical characterization studies

  • Assay determination
  • Heavy metal analysis
  • Residual solvent determination
  • Morph studies
  • Stability studies