This team provides support to discovery and process chemistry group as integrated services or as stand-alone entity to customer demands.
The various services offered in this are:
- Isolation, purification and characterization of compounds from mg to gram level.
- Chiral purification.
- High throughput purification services
- Natural product and dendrimers type purification
Structure Elucidation of Small Molecules
- Structure elucidation of new chemical entities (NCEs) by mass spectrometry, NMR (1H, 13C, 19F, 11B, 15N), IR and UV-Visible spectrophotometry.
- Higher NMR experiments like NOESY, HMBC, HMQC etc.
- MS, MS-MS, LCMS, HRMS.
- Melting point
- Log P determination
- Optical rotation
- Elemental analysis
- Stability studies by HPLC
- DSC and TGA
Regular analysis to support all chemistry services
- Routine NMR/LCMS/MS/HPLC is produced and delivered and stored through proprietary e-analytic software/database.
- Isolation of impurity
- Structure elucidation
- Data support with minute quantity
Prelinical characterization studies
- Assay determination
- Heavy metal analysis
- Residual solvent determination
- Morph studies
- Stability studies